Our co-developers and site host - Bryght - has developed a great overview guide to using this and all Drupal 4.5 sites they configure. We strongly recommend you scan through the material included here, whether you are familiar with the technology or a newbie:
Links:
[1] http://support.bryght.com/userguide
[2] http://realneo.us/help
[3] http://realneo.us/realneo-topsoil-technology-optimization-platform-for-social-organization-innovation-and-learning/help/official-drupal-guide-to-r